In order to get the effect of driving voltage waveform on the performance of squeeze piezoelectric micro droplet jetting, based on the pressure wave propagation theory of Bogy, analysis of the pressure conduction process in nozzle chamber of squeeze piezoelectric micro droplet jetting was carried out. The experimental platform of the piezoelectric micro droplet jetting system was constructed. The glycerol of 58% consistency was used as jet object in the experiments. The effects of pulse width, pulse amplitude and operation frequency of driving voltage on the performance of piezoelectric micro droplet jetting were studied. The results showed that with the increase of the pulse width of the driving voltage, the velocity and diameter of droplets were increased firstly and then decreased, there was an optimal dwell time in micro droplet jetting process; with the increase of the pulse amplitude of the driving voltage, the velocity and diameter of droplets were increased; with the increase of the operation frequency of the driving voltage, the velocity and diameter of droplets were scarcely affected in a certain range, but if the frequency was too large, the jet would be in chaos.