SAW biosensor represents one of the main trends of modern sensor technology,taking the advantages of high speed, high accuracy and sensitive to trace information in real time.The basic principal, theory and IDT structure of SAW biosensor is summarized; the technical development route of SAW biosensor is systematically outlined; the solutions for the tech convergence between SAW biosensor and SPR are discussed, and typical applications of SAW biosensor are viewed, proposing the issues needed to be solved for further engineering application.