In order to meet the requirements of the piezoelectric ceramics for the power adjustable driver and rapid response, and improve the low efficiency and large output ripple of the conventional drive power, a kind of DC inverterdriven principle and voltage control driving scheme was proposed in this paper. The theoretical analysis and practical circuit experiment were carried out. Combined with the main power circuit and control circuits, ACDC converter, the power converter, the output DC voltage rectifier filter, through the PWM control chip and sampled feedback adjusted to the duty cycle of highfrequency inverter, the size of the output voltage was regulated, and the load driving by halfbridge driver was realized. When driving an equivalent load capacitance of 6.4 μF piezoelectric ceramics, the output voltage of 0200 V is continuously adjustable at the frequency range of 01 kHz, the ripple voltage is less than 10mV and the rising time is less than 75 μs, the driving power can meet the requirement for the dispenser.