Aiming at the small flow rate problem of valveless piezoelectric pump with slopes element, a structure of valveless piezoelectric pump with taper pipe slopes element is proposed and fabricated, that is, using the new combination structure of the taper pipe and slopes element as its nonmobile components of the valve. Firstly, the structure of valveless piezoelectric pump with taper pipe slopes element is designed and its working principle is analyzed, then its flow rate of the pump is analyzed theoretically. Meanwhile, the Fluent software and its dynamic grid function is employed in simulating the flow fields of the pump. The simulation results show that the pump has a function of unidirectional flow characteristics, and fluid swirl in favor of mixing liquid inside the pump chamber. Finally, we manufactured the valveless piezoelectric pump, and the experimental results shows that the maximum flow rate of the valveless pump with taper pipe slopes element is 25.9 mL/min at a driving power supply peak voltage of 250 V and frequency of 5 Hz. These results demonstrate the feasibility of the valveless piezoelectric pump with taper pipe slopes element.